教授,博士,硕士研究生导师 研究方向:植物激素信号传导 ;植物蛋白质稳态调控 电子邮箱:lcliu@scau.edu.cn
个人简介
近年来,围绕植物激素信号传导和植物产量性状调控机制,在生长素极性运输、油菜素内酯信号传导和蛋白质质量控制领域开展了系统性研究工作。在生命科学和植物学领域主流期刊PNAS, Nature Communications, Plant Cell, Plant Physiology, Nature Genetics, Nature Plants等发表SCI论文20余篇。现任国家自然科学基金和广东省自然科学基金评审专家,《植物生理学报》编委。
承担的主要科研项目
1. 植物ABCB1的质量控制及其协同油菜素内酯信号和生长素运输的分子机制国家自然科学基金(面上项目)2020.01-2023.12 主持
2. 核苷酸单糖转运蛋白ROCK1/EBS8在拟南芥内质网蛋白质质量控制中的作用机制研究国家自然科学基金(青年项目)2017.01-2019.12 主持
3. 植物内质网介导的蛋白质降解机制国家自然科学基金(重点项目)2018.01-2022.12 参加(排名第2)
代表性论文
1.Lin L, Zhang C, Chen Y, Wang Y, Wang D, Liu X, Wang M, Mao J, Zhang J, Xing W, Liu L*, Li J* (2019) PAWH1 and PAWH2 are plant-specific components of an Arabidopsis endoplasmic reticulum-associated degradation complex. Nature Communications 10: 3492 (Co-corresponding author)
2.Liu L, Li J (2019) Communications Between the Endoplasmic Reticulum and Other Organelles During Abiotic Stress Response in Plants. Frontiers in Plant Science 10: 749
3.Xiao Y, Liu D, Zhang G, Gao S, Liu L, Xu F, Che R, Wang Y, Tong H, Chu C (2019) Big Grain3, encoding a purine permease, regulates grain size via modulating cytokinin transport in rice. Journal of Integrative Plant Biology 61: 581-597
4.Hu B, Jiang Z, Wang W, Qiu Y, Zhang Z, Liu Y, Li A, Gao X, Liu L, Qian Y, Huang X, Yu F, Kang S, Wang Y, Xie J, Cao S, Zhang L, Wang Y, Xie Q, Kopriva S, Chu C (2019) Nitrate-NRT1.1B-SPX4 cascade integrates nitrogen and phosphorus signalling networks in plants. Nature Plants 5: 401-413
5.Zhang X, Zhou L, Qin Y, Chen Y, Liu X, Wang M, Mao J, Zhang J, He Z, Liu L*, Li J* (2018) A Temperature-Sensitive Misfolded bri1-301 Receptor Requires Its Kinase Activity to Promote Growth. Plant Physiology 178: 1704-1719 (corresponding author)
6.Liu L, Tong H, Xiao Y, Che R, Xu F, Hu B, Liang C, Chu J, Li J, Chu C (2015) Activation of Big Grain1 significantly improves grain size by regulating auxin transport in rice. Proc Natl Acad Sci U S A 112: 11102-11107
7.Liu Y, Zhang C, Wang D, Su W, Liu L, Wang M, Li J (2015) EBS7 is a plant-specific component of a highly conserved endoplasmic reticulum-associated degradation system in Arabidopsis. Proc Natl Acad Sci U S A 112: 12205-12210
8.Hu B, Wang W, Ou S, Tang J, Li H, Che R, Zhang Z, Chai X, Wang H, Wang Y, Liang C, Liu L, Piao Z, Deng Q, Deng K, Xu C, Liang Y, Zhang L, Li L, Chu C (2015) Variation in NRT1.1B contributes to nitrate-use divergence between rice subspecies. Nature Genetics 47: 834-838
9.Che R, Tong H, Shi B, Liu Y, Fang S, Liu D, Xiao Y, Hu B, Liu L, Wang H, Zhao M, Chu C (2015) Control of grain size and rice yield by GL2-mediated brassinosteroid responses. Nature Plants 2: 15195
10.Tong H, Xiao Y, Liu D, Gao S, Liu L, Yin Y, Jin Y, Qian Q, Chu C (2014) Brassinosteroid regulates cell elongation by modulating gibberellin metabolism in rice. Plant Cell 26: 4376-4393
11.Liu C, Mao B, Ou S, Wang W, Liu L, Wu Y, Chu C, Wang X (2014) OsbZIP71, a bZIP transcription factor, confers salinity and drought tolerance in rice. Plant Molecular Biology 84: 19-36
12.Liang C, Wang Y, Zhu Y, Tang J, Hu B, Liu L, Ou S, Wu H, Sun X, Chu J, Chu C (2014) OsNAP connects abscisic acid and leaf senescence by fine-tuning abscisic acid biosynthesis and directly targeting senescence-associated genes in rice. Proc Natl Acad Sci U S A 111: 10013-10018
13.Tong H, Liu L, Jin Y, Du L, Yin Y, Qian Q, Zhu L, Chu C (2012) DWARF AND LOW-TILLERING acts as a direct downstream target of a GSK3/SHAGGY-like kinase to mediate brassinosteroid responses in rice. Plant Cell 24: 2562-2577
14.Sun C, Fang J, Zhao T, Xu B, Zhang F, Liu L, Tang J, Zhang G, Deng X, Chen F, Qian Q, Cao X, Chu C (2012) The histone methyltransferase SDG724 mediates H3K36me2/3 deposition at MADS50 and RFT1 and promotes flowering in rice. Plant Cell 24: 3235-3247
15.Lin A, Wang Y, Tang J, Xue P, Li C, Liu L, Hu B, Yang F, Loake GJ, Chu C (2012) Nitric oxide and protein S-nitrosylation are integral to hydrogen peroxide-induced leaf cell death in rice. Plant Physiology158: 451-464
16.Tang J, Zhu X, Wang Y, Liu L, Xu B, Li F, Fang J, Chu C (2011) Semi-dominant mutations in the CC-NB-LRR-type R gene, NLS1, lead to constitutive activation of defense responses in rice. Plant Journal 66: 996-1007
17.Sun C*, Liu L*, Tang J, Lin A, Zhang F, Fang J, Zhang G, Chu C (2011) RLIN1, encoding a putative coproporphyrinogen III oxidase, is involved in lesion initiation in rice. Journal of Genetics and Genomics 38: 29-37 (Co-first author)
18.Li C, Wang Y, Liu L, Hu Y, Zhang F, Mergen S, Wang G, Schlappi MR, Chu C (2011) A rice plastidial nucleotide sugar epimerase is involved in galactolipid biosynthesis and improves photosynthetic efficiency. PLoS Genetics 7: e1002196
19.Hu B, Zhu C, Li F, Tang J, Wang Y, Lin A, Liu L, Che R, Chu C (2011) LEAF TIP NECROSIS1 plays a pivotal role in the regulation of multiple phosphate starvation responses in rice. Plant Physiology 156: 1101-1115
发明专利
出版著作
1.《生物信息学分析实践》 科学出版社 2010 参编
2.植物生理学》科学出版社 2019 副主编
3.《科技文献检索与利用》科学出版社 2019 副主编
奖励荣誉
承担的主要课程
本科生:《生物化学》、《科研创新训练》、《生命的艺术设计》
研究生:《科技写作专题》